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Indications

Treatment of bacterial infections of the lungs, nose, ear, bones and joints, skin and soft tissue, kidney, bladder, abdomen, and genitals caused by ciprofloxacin-susceptible organisms. Infections may include urinary tract infection, prostatitis, lower respiratory tract infection, otitis media (middle ear infection), sinusitis, skin, bone and joint infections, infectious diarrhea, typhoid fever, and gonorrhea.

Administration

May be taken with or without food. May be taken w/ meals to minimise GI discomfort. Do not take w/ antacids, Fe or dairy products.

Contraindication

Hypersensitivity to ciprofloxacin or other quinolones. History or risk of QT prolongation; known history of myasthenia gravis. Concomitant use with tizanidine.

Common side-effects

Vomiting, Stomach pain, Nausea, Diarrhea

Special Precaution

Patient with known or suspected CNS disorders, risk factors predisposing to seizures, or lower seizure threshold; history or risk factors for QT interval prolongation, torsades de pointes, uncorrected hypokalaemia/hypomagnesaemia, cardiac disease (e.g. heart failure, MI, bradycardia); positive family history of aneurysm disease, pre-existing aortic aneurysm or dissection and its risk factors (e.g. Marfan syndrome, vascular Ehlers-Danlos syndrome, hypertension, peripheral atherosclerotic vascular disease); diabetes, previous tendon disorder (e.g. rheumatoid arthritis), G6PD deficiency. Renal and hepatic impairment. Elderly, children. Pregnancy and lactation.

Storage

Store between 20-25°C.

MedsGo Class

Quinolones

Drivers of Death
Generic name:

Ciprofloxacin

Caution in Patients with QT prolongation
MedsGo Class C

The risk of QT interval prolongation is approximately 25% in patients on concomitant use of ciprofloxacin and sotalol due to cystitis or prostatitis (including urinary tract infections and infections of the bones and joints), and approximately 5-fold in patients on concomitant use of tizanidine and sotalol due to pyuria.

Drug Class and Mechanism

Ciprofloxacin is a quinolone with a quinone ring and a phenol moiety. It is an inhibitor of the DNA gyrase and topoisomerase type II enzymes. It also interferes with bacterial protein synthesis. Both types of enzymes are associated with the synthesis of DNA and affect expression of messenger RNA (mRNA). Ciprofloxacin is highly potent inhibitor of DNA gyrase and type II enzymes, and it also inhibits type I and type II enzymes of bacterial ribosomal subunits. It is an irreversible DNA binding inhibitor. It also inhibits bacterial protein synthesis. The mechanism of action of ciprofloxacin is not known. The primary pharmacological action of ciprofloxacin is to inhibit the DNA gyrase and topoisomerase type II enzymes. Inhibiting these enzymes leads to inhibition of the protein synthesis of bacteria. The primary pharmacological action of sotalol is to inhibit protein synthesis in bacteria. Both sotalol and tizanidine are used in the treatment of gynocomastia. The safety and efficacy of tizanidine in the treatment of gynocomastia has not been established. Tizanidine is an anthracycline antibiotic with potent activity against gram-positive and gram-negative bacteria. It is not known whether ciprofloxacin is excreted in human milk and whether it is excreted in human milk in higher bivalent ratios. Ciprofloxacin is only excreted in milk.

The FDA approved the first drug for the treatment of bacterial and parasitic infections in the United States, and the second drug, Ciprofloxacin, will soon be approved by the Food and Drug Administration (FDA).

The antibiotic ciprofloxacin is a broad-spectrum antibiotic used to treat a wide range of infections, including:

  • infections of the gastrointestinal tract (such as diarrhea, pneumonia, and other respiratory tract infections)
  • infections caused by susceptible bacteria in the urinary tract
  • infections caused by susceptible bacteria in the skin
  • infections caused by susceptible bacteria in the eye, such as trichomonas
  • infections caused by susceptible bacteria in the ear and sinuses

The drug has a half-life of about 24 hours.

The drug is indicated for the treatment of bacterial vaginosis, a yeast infection that may cause discomfort in women who are pregnant or may become pregnant. It is also indicated for the treatment of bacterial and parasitic infections in children under 8 years old.

The drug, manufactured by GlaxoSmithKline, has a half-life of about 17 days.

This drug is in the class of medications known as fluoroquinolones.

The FDA approved the approval of ciprofloxacin as a treatment for bacterial and parasitic infections in the United States. Ciprofloxacin is an antibiotic belonging to the tetracycline class of drugs, which is used to treat infections caused by bacteria and parasites.

The medication is available in several strengths, such as 500 mg and 750 mg tablets. Ciprofloxacin is the only FDA-approved drug for the treatment of bacterial and parasitic infections.

The drug is in the class of medications known as fluoroquinolones.

The drug is indicated for the treatment of bacterial and parasitic infections in the urinary tract.

The drug is available as a tablet or capsule, and the dosage form is capsule, granule, or tablet. It is also available as a powder.

The drug is available in the form of an extended-release tablet, and the dosage form is a capsule, granule, or tablet. The drug is available in the form of an oral suspension.

The medication is available as a suspension in a liquid form.

Ciprofloxacin may be used to treat a variety of bacterial infections, including infections of the gastrointestinal tract, such as diarrhea and pneumonia, as well as anaerobic infections, such as the following infections:

  • infections caused by susceptible bacteria in the eye

Ciprofloxacin can be used to treat certain infections caused by susceptible bacteria in the urinary tract, such as UTI, pneumonia, or gonorrhea. The drug can also be used to treat infections caused by gonorrhea or other sexually transmitted infections.

Ciprofloxacin is not approved for use by pregnant women and is not recommended for use by breastfeeding women.

The drug is indicated for the treatment of infections caused by susceptible bacteria in the urinary tract, including gonorrhea and some other sexually transmitted infections.

The drug is indicated for the treatment of infections caused by susceptible bacteria in the skin, such as trichomonas, which can cause discomfort in women who are pregnant or may become pregnant. It is also indicated for the treatment of infections in children under 8 years old.

The drug is indicated for the treatment of certain bacterial infections caused by susceptible bacteria in the urinary tract, including gonorrhea and some other sexually transmitted infections.

The drug is indicated for the treatment of infections in children under 8 years old, including infections caused by susceptible bacteria in the urinary tract.

The drug is indicated for the treatment of infections caused by susceptible bacteria in the eye, such as trichomonas, which can cause discomfort in women who are pregnant or may become pregnant.

Consumer Medicine Information (CMI) summary

What is in this document?

OVERVIEW:

CIPROFLOXACIN HYDROCHLORIDE (CIPRO) is a synthetic antibacterial that belongs to the fluoroquinolone class of antibiotics. CIPRO is a type of drug that inhibits the DNA synthesis of bacteria.

History and Clinical Significance

CIPRO is a type of antibiotic that belongs to the fluoroquinolone class of antibiotics. It is used for the treatment of various infections caused by susceptible bacteria. CIPRO is effective against a variety of bacterial and fungal infections, including urinary tract infections, bronchitis, tonsillitis, and pneumonia.

Mechanism of Action

CIPRO inhibits bacterial DNA synthesis by inhibiting the bacterial enzyme, DNA polymerase. This action leads to the synthesis of bacterial DNA.

Pharmacological Actions

CIPRO is a broad-spectrum antibiotic that inhibits the synthesis of bacterial DNA.

Use in Pneumonia

CIPRO is used for the treatment of acute bacterial exacerbation of chronic bronchitis (AECB) and community-acquired pneumonia (CAPC). It is also used to treat other infections caused by bacteria.

Side Effects

Common side effects of CIPRO may include:

CIPRO may also cause mild to severe allergic reactions, including rash, itching, and swelling.

Precautions

CIPRO should be used with caution in individuals with a history of liver disease or jaundice.

Pregnancy and Breastfeeding

CIPRO may be prescribed for use during pregnancy by the FDA only. CIPRO should not be used by breastfeeding women.

Adverse Reactions

CIPRO may cause a range of adverse reactions that are reversible, and may include:

CIPRO may cause or worsen side effects that can be severe. These may include:

Serious skin reactions such as Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) may occur during CIPRO treatment. CIPRO should be used with caution in the following cases:

Rash and/or itching are more common in patients with known or suspected hypersensitivity to CIPRO or any of its components:

Increased incidence of SJS has been reported in patients with a history of SJS and TEN. Although these reactions are generally reversible, patients may experience a few weeks or more of symptoms that may require immediate medical attention.

CIPRO should be used with caution in patients who are pregnant or may become pregnant. CIPRO should not be used by women who are breast-feeding.

CIPRO may cause a range of adverse reactions that can be severe and may include:

The safety and effectiveness of CIPRO during pregnancy has not been established.

CIPRO should be used only when the benefits outweigh the risks.

Interactions

Inform your doctor about all medications, supplements, and herbal products you are taking to prevent CIPRO interactions.

CIPRO may cause or worsen side effects that can be serious.

Pregnancy Warnings

CIPRO should be used with caution in pregnant women and nursing mothers. CIPRO should be used with caution in nursing mothers and children as well.

Product Description

Cipro 500mg Tablets

Cipro 500mg Tablets, also known as Ciprofloxacin, is a medication containing ciprofloxacin, commonly known as ciprofloxacin. It belongs to a class of drugs known as fluoroquinolones. Ciprofloxacin is used to treat bacterial infections. It can be used for the treatment of urinary tract infections, respiratory tract infections, skin and soft tissue infections, and certain types of respiratory tract infections. Ciprofloxacin is available in the form of oral tablets.

Ciprofloxacin belongs to the fluoroquinolone class of antibiotics. It works by inhibiting bacterial DNA gyrase, an enzyme that breaks down the DNA of bacteria. This results in the death of bacteria, allowing the bacteria to live longer and help them heal.

Key Features

  • Effective Antibiotic: Ciprofloxacin is an effective antibiotic that is used to treat a wide range of bacterial infections.
  • Dosage: Ciprofloxacin is available in a 500 mg tablet form.
  • Side Effects: Some people may experience side effects such as nausea, vomiting, or diarrhea when taking this medication. It is essential to consult with a healthcare professional before using it.
  • Potential Side Effects: Some people may experience mild side effects such as skin rash, nausea, or diarrhea when taking this medication.
  • How to Use: Take the tablet by mouth with or without food. Swallow the tablet with a glass of water. Do not crush or chew the tablet.
  • Precautions: Do not take Ciprofloxacin if you have certain medical conditions, such as liver or kidney problems, severe stomach or intestinal disease, or if you are allergic to ciprofloxacin, other antibiotics, or other ingredients in Ciprofloxacin.
  • Possible Side Effects: These side effects may include nausea, vomiting, diarrhea, headache, and rash.
  • Storage: Store Ciprofloxacin at room temperature, away from moisture and heat.
  • Precautions: Do not use this medication if you are pregnant or breastfeeding, or if you have any of the following conditions: Heart disease, stroke, or high blood pressure.
  • Interactions: Ciprofloxacin may interact with certain medications and health conditions, so it is important to inform your healthcare provider of all medications you are taking.

Product Information

Manufacturer Information

Cipro 500mg Tablets is a brand of the antibiotic Ciprofloxacin.

The medication comes in different strengths, and it is important to follow the recommended dosage and to take the medication exactly as prescribed by your doctor. The recommended dosage of Ciprofloxacin for treating bacterial infections is 500 mg per day.

The generic version of Ciprofloxacin is Cipro 500mg. Cipro 500mg Tablets is available in the form of tablets, and it is important to follow the instructions carefully and take it as directed by your doctor. The dosage of Ciprofloxacin for treating bacterial infections depends on the severity of the infection, your age, and any other medical conditions that you may have. It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

The medication is available in the dosage strengths of 500 mg to 1000 mg and it is important to follow the dosage instructions carefully. It is important to take this medication exactly as directed by your doctor.

The medication is available in the dosage strengths of 250 mg to 500 mg. It is important to follow the recommended dosage and to take the medication exactly as prescribed by your doctor.